SAMe

• Vegan

• Non GMO

• Vegetarian

• Helps relieve pain due to osteoarthritis

• Helps to promote healthy mood balance

• Made with hypoallergenic, vegan ingredients

• Manufactured using a solvent-free manufacturing process

• Provides 200 mg per capsule of enhanced-stability form SAMe

SAMe (S-adenosylmethionine) is a Metabolic Aid present in all living cells. It functions as a donor of methyl groups in over 100 different reactions and contributes to the synthesis, activation and/or metabolism of hormones, neurotransmitters, nucleic acids, phospholipids, and proteins. Methyl groups act as a signal throughout the body, regulating genetic expression and cellular function. SAMe also promotes healthy mood balance, as indicated in over 40 clinical studies. In a meta-analysis involving 25 controlled trials and 791 individuals, SAMe offered statistically significant Aid for positive mood, believed to be due to its Aid for neurotransmitter monoamine synthesis and function, including dopamine and serotonin. It also promotes healthy protein turnover and maintains healthy phospholipid methylation to Aid phosphatidylcholine production and cellular membrane integrity and fluidity. Studies suggest it Aids joint flexibility and comfort in individuals with osteoarthritis as well. In a meta-analysis involving 11 studies, SAMe offered statistically significant Aid for joint function. It is believed to relieve osteoarthritis pain by Aiding proteoglycan synthesis, as well as helping to stabilize and Safeguard the proteoglycans.

Medicinal Ingredients

(per capsule):

SAMe (from S-Adenosyl-L-methionine disulfate tosylate) 200 mg.

Non-Medicinal Ingredients

Vegetarian capsule (hypromellose, water), Hypoallergenic plant cellulose, Calcium oxide, Ascorbyl palmitate, Calcium chloride.

Recommended Dose

Adults: For healthy mood balance, take 2 capsules 1-3 times daily. For osteoarthritic pain, take 2 capsules 3 times daily. Take in divided doses, between meals, or as directed by a healthcare practitioner. For osteoarthritic pain, use for a minimum of 8 weeks to see beneficial effects. Consult a healthcare practitioner for use beyond 12 weeks.

Warning

Do not use if you are pregnant, breastfeeding or have been diagnosed with bipolar disorder. Consult a healthcare practitioner prior to use if you are taking medication such as antidepressants, hepatoxic drugs or monoamine oxidase (MAO) inhibitors. Do not take at night, as the product may cause anxiety, restlessness and insomnia. Consult a healthcare practitioner if symptoms persist or worsen. Some people may experience mild gastrointestinal upsets, anxiety, restlessness, insomnia, hyperactive muscle movement, and hypomania, in which case discontinue use and consult a healthcare practitioner.

Store sealed in a cool dry area. Use only if safety seal is intact.

Orders within the USA qualify for FREE SHIPPING if the pre-tax subtotal is over $99.

International orders are shipped via DHL or Canada Post, with any additional customs clearance fees, tariffs, and charges being the responsibility of the customer.
All international and U.S. orders are final sale and cannot be returned.

All communication with international customers outside of the USA will be handled via email only.

Please Note:
• Orders may experience delays during holiday seasons or statutory holidays.
• Liquids in glass containers shipped through Canada Post may not be insured and are shipped at the recipient's risk.