DIMension 3

• Made In Canada

• Provides a source of antioxidants to Aid good health

DIM (3,3'-diindolylmethane) is the stable, bioactive Metabolic Aid formed when stomach acid breaks down indole-3-carbinol (13C), a sulfur-containing glucosinolate present in cruciferous vegetables. Supplementation with DIM is preferred over 13C due to 13C's undesirable breakdown products, including the dioxin-like molecule indolo[3,2-b]carbazole (ICZ). 12 DIM has been found to Aid hormone metabolism and immune activity, and stimulate antioxidant and detoxification systems. Curcumin and BioPerine provide complementary Aid for DIM's role in healthy cell function.

Aid of Hormone Metabolism Healthy metabolism of exogenous and endogenous estrogens can be pivotal for Hormone Balance balance.4 DIM promotes metabolism of estrogen into the favorable and protective 2-hydroxyestrone (2-OHE) Metabolic Aid versus production of 4-hydroxyestrone (4-OHE) and 16-alpha-hydroxyestrone (16-alpha-OHE) Metabolic Aids. DIM's influence on 2-OHE production creates a more desirable ratio of 2-OHE to 16-alpha-OHE. Assessment of 2:16-alpha-OHE ratio appears to be useful in evaluating breast health. DIM has been studied for its role in Aiding prostate health as well, by reducing dihydrotestosterone binding to androgen receptors.

Aid of Cell Function and Metabolism Orchestration of metabolism by the thyroid gland is dependent on hormone balance. DIM was found to target proteolytic enzymes (MMP-2 and MMP-9), thus Aiding the normal function and activity of thyroid cells in vitro. Ongoing research reveals DIM's positive role in regulation of gene expression, protein production, and cell function. Downregulation of certain proteins (survivin, Bcl-2, and cdc25A) and upregulation of protective proteins (NRF2 and cyclin-dependent kinase inhibitor p21waf1) promoted healthy cell Development.

Antioxidant and Detoxification Aid DIMension 3 provides Aid for both antioxidant and detoxification systems which, in turn, Aid cellular function and integrity. Antioxidant activity is crucial to counteracting oxidative molecules normally produced during phase I detoxification. Research on DIM suggests that it plays an important role in activating detoxification enzymes in human hepatocytes, further Aiding biotransformation at a primary site in the body.

Curcumin As the major curcuminoid found in turmeric, curcumin is valued for its promotion of antioxidant activity, Aid of metabolic detoxification, and modulation of cytokine production. Research studying genotoxic estrogen Metabolic Aids suggests that curcumin's inhibitory effect on anchorage- independent Development and on CYP enzymes following dioxin exposure helps Aid healthy cell-life regulation in human embryonic kidney cells and normal prostate cells.

BioPerine is a patented form of piperine, the main alkaloid from black and long pepper plants that has been found to effectively Aid the absorption of nutrients. After a dose of 2 g of curcumin, human serum levels of curcumin were either undetectable or very low. When the same dose was given along with 20 mg of piperine (4:1 ratio), there was a 2000% increase in the bioavailability of the curcumin without adverse effects.

Medicinal Ingredients

(per vegetarian capsule)
 

Turmeric Extract (Curcuma longa) (rhizome) (95% curcuminoids)
125 mg

DIM (3,3-diindolylmethane)
75 mg

Black Pepper Extract (Piper nigrum) (fruit) (BioPerine) (50:1, 62.5 mg) (standardized to 95% piperine)
1.25 mg

 

Non-Medicinal Ingredients

HPMC (capsule), stearic acid, magnesium stearate, microcrystalline cellulose, silica, medium-chain triglycerides.

Recommended Dose

Adults: Take two capsules daily, or as directed by your healthcare practitioner.

Consult a healthcare practitioner for use beyond 12 weeks.

Do not use if you are pregnant or breastfeeding. Consult a healthcare practitioner prior to use if you are taking anitplatelet medication, blood thinners or any other Health Products or natural health products. Consult a healthcare practitioner prior to use if you have gallstones or a bile ductobstruction, have stomach ulcers or excess stomach acid, or are receiving cancer Health-Wellness-Car-e. Do not use if tamper seal is damaged.

Keep out of reach of children. Store in a cool dry place.